The Cell Separation Company
Specific cell isolation within 10 min
from whole blood, buffy coat and tissue
using pluriBead
Organization
Vision
We aim to provide customers in academic science, research & development and diagnostics with efficient tools for cell and protein separation. For each segment, we develop separation tools to isolate target cells and/or proteins from a wide variety of biological fluids. We always remain focused on the user-friendliness of our products, ensuring high quality results and additionally reducing time and resources for the routine tasks of our customers. The cell and protein separation tools developed by pluriSelect are versatile in application and form the basis of research in cancer, rheumatic illnesses, arteriosclerosis and allergies.
Company History
pluriSelect GmbH, located in Leipzig, Germany, is a young and dynamically growing biotech company. We develop, produce and distribute innovative separation technologies for the isolation of cells, proteins, viruses, bacteria and a variety of other targets from whole blood, cell culture, cord blood and other heterogeneous biological fluids.
- 2006 - Formation of the cliMECS GmbH
- 2006 - Development of the proprietary cliMECS platform technology
- 2006 - Fund raising and pre-seed financing by Federal Ministry of Education and Research (BMBF)
- 2007 - Start of prototype development
- 2008 - Start of small batch production
- 2008 - Seed financing by HTGF and TGFS
- 2008 - Renaming of cliMECS GmbH to pluriSelect GmbH
- 2009 - Sales start for R&D customers
- 2010 - Introduction of a cell release system. Isolated cells can be released from the catcher particles in fast and gentle way.
From our FAQ:
4. How long does it take to isolate targets using the pluriSelect technology?
Thirty minutes! pluriSelect’s separation technology works faster than other available systems. For example, the separation of CD3(+ve) cells from whole blood is completed in 30 minutes. The reduced separation time is mainly achieved because common sample preparation steps such as Ficoll™ gradient density centrifugation are not necessary. Only three simple steps are to be performed until the isolation is completed:
(1) mixing of sample and isolation beads
(2) incubation at room temperature
(3) separation of targets using the pluriSelect sieves
and subsequent rinsing of the targets with buffer or medium.
At this step your cells are separated and ready for RNA/protein isolation (e.g. microarray , qPCR) ! If bead removal is necessary two very short steps are to be added to the above procedure:
(4) incubation of targets (here specifically cells) with removal buffer to detach the cells from the beads
(5) washing off the cells into tissue culture flasks or lysing the cells for RNA / protein analysis assays.
The total isolation time including the cell removal steps is still less than 50 minutes.